Teas and tinctures that blend false unicorn root with other so-called "female" herbs (wild yam and chasteberry, for example) are billed as tonics for fortifying the reproductive organs. Some herbalists recommend the root for menopausal symptoms and to treat ovarian cysts. It has even been recommended for normalizing hormone levels following oral contraceptive use.

False unicorn root was once popular for preventing miscarriage; Native American women reportedly chewed the root for this purpose. It was also used to treat vomiting from pregnancy.